Yashoda Hospitals > Medicine FAQS > Selegiline

Selegiline: Frequently Asked Questions Answered

What is Selegiline?

Selegiline is an enzyme blocker (Monoamine oxidase or MAO inhibitor). A dose of Selegiline helps slow the breakdown of neurotransmitters such as dopamine, norepinephrine, and serotonin. Selegiline is used to control the symptoms of Parkinson’s disease in people who are taking a levodopa and carbidopa combination. It helps by decreasing the dose of levodopa/carbidopa, stops their effect from wearing off between doses, and increases the length of time that the medicational combination controls symptoms.

What Are The Uses Of Selegiline?

In people on a levodopa and carbidopa dose combination for their Parkinson’s disease (a disorder of the nervous system that causes difficulties with movement, muscle control, and balance), Selegiline is used to help control the symptoms. Although it does not cure Parkinson’s, it may improve tremor, muscle stiffness, and loss of normal movement and improve range of motion and ability to walk, dress, and exercise.

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    What Are The Side Effects Of Selegiline?

    Dizziness, fainting, heartburn, constipation, dry mouth, nausea, stomach pain, and vomiting are some of the common side effects of Selegiline. Others include difficulty falling asleep or staying asleep, pain, rash, and sores in the mouth. More severe side effects are sweating, pounding heartbeat, uncontrollable shaking of a part of your body, unusual movements that are difficult to control, and trouble breathing.

    Talk to your doctor to know the side effects and precautions before taking this drug.

    What is Selegiline

    Uses of Selegiline

    Side effects of Selegiline

    References

    1. medlineplus.gov
    2. https://www.ncbi.nlm.nih.gov/books/NBK526094/
    3. https://pubmed.ncbi.nlm.nih.gov/16420301/
    4. drugs.com

    Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.

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    Frequently Asked Questions about Selegiline

    Selegiline is an enzyme blocker used in the treatment of Parkinson’s disease. The drug can take up to a few weeks to be effective, but improvements are noticeable within a few days of taking it. Selegiline is taken orally, usually with breakfast and lunch (taking it later in the day may cause sleep problems).

    Selegiline is not a scheduled controlled substance. It is available on prescription. In some countries, Selegiline is considered a controlled substance because of the drug’s structural similarity to amphetamine.

    Selegiline is an enzyme blocker (or MAO inhibitor). One of its primary uses is to control the symptoms of Parkinson's disease.

    Selegiline may cause a hypertensive crisis if taken with food, drink, or supplements rich in tyramine (an amino acid found in the body and certain foods that help regulate blood pressure)—consuming tyramine while on Selegiline can raise your blood pressure to dangerous levels that could have life-threatening side effects.

    Selegiline, an enzyme blocker, is a Monoamine oxidase or MAO inhibitor. A dose can reduce the rate of the breakdown of neurotransmitters serotonin and dopamine. Selegiline is used to control the symptoms of Parkinson's disease in people who are on a levodopa/carbidopa combination.

    Selegiline belongs to the drug class of Dopaminergic antiparkinsonian agents and Monoamine oxidase inhibitors. Among its primary uses is that it prevents the breakdown of dopamine, low levels associated with Parkinson's disease. Although it does not cure Parkinson’s, it improves tremors, muscle stiffness, and loss of movement.

    Selegiline is used to treat certain conditions in dogs, such as pituitary-dependent Cushing's disease (condition when adrenal glands oversecrete cortisone) and senile mental deterioration (loss of cognitive function).

    Selegiline, a monoamine oxidase B (MAO-B) inhibitor, has been shown to alleviate anxiety symptoms. Some reports have shown that oral Selegiline treatment may be effective in treating depression. The drug has also been effective for depressive and anxiety symptoms in people living with Parkinson’s disease.

    The enzyme blocker Selegiline, a monoamine oxidase B (MAO-B) inhibitor, has been shown to exert significant antidepressant effects and improve anxiety levels. A dose of Selegiline helps slow the breakdown of neurotransmitters such as dopamine, norepinephrine, and serotonin.

    Selegiline, an MAO inhibitor, has been shown to cause a hypertensive crisis if taken with food, drink, or supplements rich in tyramine (an amino acid found in the body and certain foods that help regulate blood pressure)—eating tyramine while on Selegiline can raise blood pressure to dangerous levels.

    One of the main precautions to adhere to is not mixing Selegiline with other medications without consulting your doctor. Some products that may interact with Selegiline include antidepressants, other MAO inhibitors, cold medications/nasal decongestants, stimulants, appetite suppressants, supplements containing tyramine, etc.

    The Yashoda Group of Hospitals believes in providing quality healthcare. Over the years, it has evolved as a center of excellence in medicine, providing the highest quality standards of medical treatment to all sections of society. Our medical experts are always on call to help answer queries regarding drugs' uses, precautions, dose, and side effects. Do call us if you need assistance.