Yashoda Hospitals > Medicine FAQS > Hesperidin

Hesperidin: Frequently Asked Questions Answered

What is Hesperidin?

Hesperidin is a plant-derived natural medicine. Hesperidin was first extracted from the whitish layer underneath the peel of an orange in 1828 by French chemist Lebreton. Hesperidin is a flavonoid, meaning it is a phenolic compound- bound to sugar as glycosides formulations. Hesperidin is commonly extracted from citrus fruits such as lemons and oranges. Lime and grapefruit are also considered to be rich sources.

What are the uses of Hesperidin?

Our body breaks down Hesperidin into its chemically active form called hesperetin by removing the attached sugar. Hesperetin acts as an antioxidant, anti-inflammatory, and a mild anti-allergic. It is given as supplements along with diosmin to treat patients with circulatory problems such as haemorrhoids, leg sores, and swelling in the legs due to venous insufficiency. Uses of Hesperidin in other disease processes such as obesity and hypertension are under active research.

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    What are the side effects of Hesperidin?

    Hesperidin is generally considered to be a safe supplement. Precautions are advisable in patients with coagulation and hypertensive disorders. 

    Administration of Hesperidin commonly causes:

    • Abdominal pain
    • Upset stomach and diarrhoea
    • It can also slow blood clotting.

    Therefore, it must not be taken by patients immediately after surgery. Consult a physician before taking Hesperidin. Do not increase or decrease the dose without proper recommendations.

    What is Hesperidin

    Uses of Hesperidin

    Side effects of Hesperidin

    References

    1. Hesperidin: Health Benefits, Side Effects, Uses, Dose & Precautions (rxlist.com)
    2. Hesperidin | C28H34O15 – PubChem (nih.gov)
    3. Hesperidin: Uses, Interactions, Mechanism of Action | DrugBank Online
    4. Hesperidin Supplement — Health Benefits, Dosage, Side Effects | Examine.com
    5. Hesperidin: synthesis and characterization of bioflavonoid complex | SpringerLink
    6. Hesperidin: Benefits, Side Effects, Dosage, and Interactions (verywellhealth.com)

    Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.

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    Frequently Asked Questions about Hesperidin

    Hesperidin is a flavonoid derived from peels of citrus fruits. Lemons, oranges, lime, and grapefruit are considered to be rich sources of Hesperidin. Obtaining therapeutic quantities of Hesperidin naturally from the consumption of oranges is quite difficult. Sun-dried peels of tangerines and oranges can deliver good amounts of Hesperidin to the body.

    In an average serving of orange juice, 30-130 mg of Hesperidin is said to be present. However, it is not possible to obtain enough Hesperidin simply by the consumption of citrus fruits. Consuming sun-dried peels of tangerines and oranges is advised to get Hesperidin naturally.

    No. Hesperidin is a flavonoid and not a carotenoid. While both flavonoids and carotenoids are derived from plants, carotenoids can also be extracted from some bacteria and fungi. Carotenoids are said to be present in the chloroplasts of plants. Flavonoids are simply phenol compounds that can be extracted from various plant parts.

    Hesperidin methyl chalcone is found in the pulp, membranes, and peels of citrus fruits. As a bioflavonoid, it is soluble in water and is used in the treatment of venous insufficiencies. To get more information about the uses of Hesperidin methyl chalcone, get the best medical opinion from our experts.

    Adaptogens are naturally derived chemicals from herbs and mushrooms that can help cope with stress and anxiety. Hesperidin is also used as an adaptogen and an antidepressant. However, these uses of Hesperidin are not well-researched. Consult our expert to know more about the uses of Hesperidin.

    Yes. Hesperidin can act as a blood thinner. It can slow down the process of blood coagulation. And for this reason, Hesperidin is not recommended to people suffering from bleeding disorders or taking anticoagulants. Hesperidin is also not recommended after undergoing surgery to prevent bleeding complications.

    Research data on the benefits of Hesperidin in the treatment of hypertension is insufficient. While some research data suggests that a daily dose of Hesperidin can reduce blood pressure, others indicate that Hesperidin is not entirely helpful. Hesperidin generally reduces diastolic blood pressure more than systolic blood pressure.

    Yes. Hesperidin is generally derived from peels of citrus fruits such as lemons and oranges.

    It is also present in the pulp and membranes of these citrus fruits. Lemon juice also contains Hesperidin, but lemon juice alone cannot compensate for the need for Hesperidin medicines.

    Hesperidin is not considered safe for patients already taking anticoagulants, calcium channel blockers, or suffering from hypertension because it acts as a blood thinner. In other cases, Hesperidin is considered safe for use up to six months and does not cause serious side effects other than mild gastrointestinal upset.

    The duration of treatment using Hesperidin depends on the condition treated. Hesperidin and diosmin are administered for two months for leg ulcers and three months to treat anal haemorrhoids. Get help from our experts now to know the doses of Hesperidin best suited for you.

    Click here to consult our medical expert available 24*7 at Yashoda Hospitals to clarify your queries and answer any medical concerns that remain unanswered concerning Hesperidin or any other medical question.