Yashoda Hospitals > Medicine FAQS > Canagliflozin

Canagliflozin: Frequently Asked Questions Answered

What Is Canagliflozin?

Canagliflozin comes from a category of medicine known as sodium-glucose co-transporter 2 (SGLT2) inhibitors. Canagliflozin is usually used alongside recommended diet and exercise to lower blood sugar levels in people with diabetes. It will not lessen the danger of stroke, attack, or death in people with type 2 diabetes alongside heart and vessel disease. Canagliflozin additionally won’t diminish the threat of end-stage renal disorder, worsening of kidney function, hospitalization for coronary failure, and cardiovascular death in people with type 2 diabetes alongside severe renal illness. It lowers blood glucose by causing the kidneys to urge to obviate more glucose within the urine.

What Are The Uses Of Canagliflozin?

Canagliflozin comes in tablet form, and patients are typically prescribed a dose of the medicine with regular exercise and a nutritious diet. Canagliflozin tablet use lowers blood sugar levels in patients with type 2 diabetes. Patients at risk of stroke, heart attack, or signs of kidney disease can also be prescribed a Canagliflozin tablet. Canagliflozin is not used to treat patients with type 1 diabetes; however, it can lower the sugar amount in urine.

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    What Are The Side Effects Of Canagliflozin?

    Frequent urination, unusual dry mouth, dizziness, and lightheadedness are some of the most common side effects of Canagliflozin tablets. Regular usage of Canagliflozin may cause yeast infection in the vagina or penis. Although Canagliflozin does not cause low blood sugar levels, it may occur if this medicine is prescribed along with other medications that treat the exact root cause. Itching in the vagina due to yeast infection can be an early manifestation of the disease.

    What is Canagliflozin

    Uses of Canagliflozin

    Side effects of Canagliflozin

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    Frequently Asked Questions about Canagliflozin

    Canagliflozin falls into the category C drugs, according to the FDA. If taken during pregnancy, it may produce potential risks for the unborn child. Thus, it is better to inform your doctor prior if you’re planning a pregnancy. It may cause defects in the body of the unborn child, thus being cautious is necessary.

    A higher than usual rate of bone fracture and a case of low bone mineral density are observed in people who intake regular units of Canagliflozin. Although the exact reason is not found yet, chances of decreased bone density (at the lumbar spine and hip )and osteoporosis have been reported.

    Canagliflozin, the active ingredient of Invoka, is chemically known as (1S)-1,5-anhydro-1-[3-[[5-(4-fluorophenyl)-2-thienyl]methyl]-4-methylphenyl]-D-glucitol hemihydrate, and its molecular formula and weight are C24H25FO5S•½ H2O and 453.53, respectively.

    Based on the reports from two clinical trial giants, the US Foods and Drug Administration (FDA) officially stated that the increased and prolonged use of the Canagliflozin tablet causes amputated feet and legs. However, if monitored, this can be checked easily.

    According to studies, Canagliflozin did not give any unusual side effects when used on patients with CKD. It lowered the blood sugar level, reduced body weight and blood pressure, and was overall well-tolerated.

    Canagliflozin comes from a class of drugs called sodium-glucose co-transporter 2 (SGLT2) inhibitors. It is used to reduce the levels of glucose in your blood level. It is used in type 2 diabetes and is prescribed by a trained medical practitioner. It is available in the form of tablets.

    Canagliflozin works in the kidneys to prevent the absorption of glucose, assisting better absorption of sugar. Metformin lessens glucose absorption from the stomach, reduces stored glucose from the liver, and helps the body use glucose better. Usually, a combination of both is prescribed for patients who have type 2 diabetes.

    No, Canagliflozin is not a generic drug. Canagliflozin belongs to a class of medications called sodium-glucose co-transporter 2 (SGLT2) inhibitors. The medicine is prescribed to patients with type-2 diabetes, risk of stroke, heart attack, or have signs of kidney disease.

    Patients who are insulin-dependent and have type-1 diabetes and patients with chronic renal failure should not take Canagliflozin. It is contraindicated in pregnancy and chronic heart failure. These patients are at high risk of developing side effects; thus, they should not take the medicine.

    Although weight gain is not an actual effect of the Canagliflozin, it can be a side effect in a few patients. Cases of weight gain are rare, but on the contrary, weight loss is one of the direct effects of taking Canagliflozin.