What is CSF Test?

Cerebral Spinal Fluid (CSF) is a clear and colourless fluid that is present in your brain and spinal cord. The Central Nervous System is made up of the Brain and Spinal Cord that performs various functions. This includes complex thinking, muscle movement, and organ function. CSF controls all these functions. It also clears the waste in your brain and helps it to function well.

The Cerebral Spinal Fluid (CSF) is a set of tests done to analyse if you have any serious conditions or diseases in your brain or spinal cord. 

Let us read further to know this test in detail, its procedure and test results.

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    Frequently Asked Questions

    The set of CNS tests is done to analyse:

    • Infectious diseases of the brain and spinal cord, such as meningitis and encephalitis. 
    • The ranges of white blood cells, bacteria, and other substances in the cerebral spinal fluid.
    • Autoimmune disorders including multiple sclerosis (MS) and Guillain-Barré Syndrome. 
    • Bleeding in the brain.
    • Brain tumours.

    Components

    Normal Ranges

    Antibodies and DNA of common viruses

    None

    Myelin basic protein

    Less than 4ng/mL

    Opening pressure

    90 to 180mm of water

    Cancerous cells

    No cancerous cells present

    Cell count: 

    WBC: less than 5 and RBC: 0

    Chloride

    110 to 125 mEq/L

    Glucose

    50 to 80 mg/dL 

    Glutamine

    6 to 15 mg/dL

    Lactate dehydrogenase

    less than 40 U/L

    Oligoclonal bands

    0 or 1 bands

    Protein

    15 to 60 mg/dL (

    The abnormal ranges of your CSF test may indicate:

    • Infection
    • Inflammation
    • Reye syndrome
    • MeningitisMultiple sclerosis (MS)
    • Cancer
    • Encephalitis
    • Hepatic encephalopathy

    You may need a CSF test if you experience the following symptoms:

    1.Infections in brain or spinal cord:

    • Severe headache
    • Double vision
    • Changes in behaviour
    • Stiff neck
    • Nausea and vomiting
    • Sensitivity to light

    2. Autoimmune disorder, such as multiple sclerosis (MS):

    • Bladder control problems
    • Muscle spasms
    • Weak muscles
    • Dizziness

    For further interpretation of the results, consult your doctor and get the earliest treatment.

    A procedure called Spinal Tap or Lumbar Puncture is done to collect your Cerebral Spinal Fluid. The procedure is usually done at the hospital. This includes the following steps:

    • First, your doctor asks you to lie flat or on your side.
    • Your health care expert cleans your back and inject an anaesthetic so that you don't feel pain during the process.
    • Once the area is completely numb, the professional inserts a thin, hollow needle between the two vertebrates( bones that make up the spine) of your lower spine. 
    • He collects some amount of cerebrospinal fluid for examination. But you need to stay still while the professional collects the sample as it may lead to a risk of bleeding.
    • After the sample is collected, you will be advised to lie straight on your back.
    • Your sample is then sent to the laboratory for testing.

    After the test is complete, it is sent to the laboratory for examination. Your doctor will ask you to lie flat for one hour after the lumbar puncture or spinal tap. You may develop a headache after the spinal tap. Your doctor may advise you to drink caffeinated beverages such as coffee, tea, or soda if it happens.

    The CSF test may detect the following:

    1. Infections of brain or spinal cord such as
    • Encephalitis
    • Meningitis
    • West Nile virus
    • Eastern equine encephalitis virus (EEE) 
    • Tuberculosis.
    1. Autoimmune disorders such as
    • Multiple sclerosis
    • Guillain-Barre syndrome 
    • Sarcoidosis.
    1. Bleeding in the brain
    2. Brain tumours

    CSF leaks can be caused by an injury, an epidural, surgery, a spinal tap or a tumour. Many CSF heal on their own, but those don't require surgical repair.

    The CSF test is an easy, quick and effective series of tests done to find the serious conditions or diseases that develop in your brain or spinal cord. The whole procedure takes between five minutes to one hour.

    Your health care expert will guide you through the preparations before the test. However, it is generally advised to empty your bladder and bowels before the test.

    CSF test may have the following risks involved:

    • People who are given blood thinners may bleed
    • An infection at the puncture site
    • A headache after the test
    • Discomfort during and after the procedure
    • An allergic reaction to the anaesthetic.

    If you have any queries, feel free to book an appointment with our specialists and get a medical opinion.