Yashoda Hospitals > Medicine FAQS > Drotaverine

Drotaverine: Frequently Asked Questions Answered

What is Drotaverine?

Drotaverine is an antispasmodic medication used to relax smooth muscles such as the muscles of the stomach and heart. It is structurally linked to Papaverine, has no anticholinergic effects, and is a selective phosphodiesterase 4 inhibitor. It eases IBS, headaches, menstrual cramps, duodenal ulcers and to relieve cervical spasm during childbirth. Drotaverine is also used to treat biliary dyskinesia, benign prostatic hyperplasia or BPH, and other vasomotor diseases.

What are the uses of Drotaverine?

Drotaverine is used to alleviate smooth muscle spasms in organs, including the heart and stomach. Drotaverine is primarily used to relieve painful spasms related to chronic gastroduodenitis, gastric or duodenal ulcers, irritable darkness syndrome (intestinal disease leading to cramps in the abdomen), and many other stomachs intestine disorders linked with severe spasms. It may also be taken during menstruation to alleviate discomfort (dysmenorrhea).

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    What are the side effects of Drotaverine?

    Some of Drotaverin’s frequent and severe adverse effects are:

    • Nausea
    • Vomiting
    • Dry body
    • Pulse rate change
    • Dizziness
    • Headache
    • Breathing difficulty
    • Allergic to the skin
    • Face, lips, eyelashes, and tongue swelling
    • Blood pressure drop
    • Vertigo
    • Constipation
    • Disturbed sleep
    • Dermatitis

    You can consult our medical experts at Yashoda Hospital. They can guide you on the uses and benefits, along with the appropriate dosage and precautions of Drotaverine.

    What is Drotaverine

    Uses of Drotaverine

    Side effects of Drotaverine

    References

    1. https://www.sciencedirect.com/science/article/abs/pii/S0020729203002765
    2. https://bjuijournals.onlinelibrary.wiley.com/doi/abs/10.1046/j.1464-410X.2003.04262.x

    Disclaimer: The information provided herein is accurate, updated and complete as per the best practices of the Company. Please note that this information should not be treated as a replacement for physical medical consultation or advice. We do not guarantee the accuracy and the completeness of the information so provided. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company. We do not take any responsibility for the consequences arising out of the aforementioned information and strongly recommend you for a physical consultation in case of any queries or doubts.

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    Frequently Asked Questions about Drotaverine

    Yes, Drotaverine is a pain-relieving medication for spasms. It is used to alleviate abdominal and stomach aches from mild to severe. It also relieves menstrual cramping and pain caused due to kidney or biliary stones or any gastro-intestinal colicky pain. However, the dosage must be taken only as prescribed by the doctor.

    One tablet of Drotaverine contains 40 mg of Drotaverine Hydrochloride. It is an efficient and safe pharmacological medication for treating childhood recurring stomach discomfort.

    No, Drotaverine is not recommended to patients suffering from liver dysfunction. Patients with liver function impairment should take any medication with care. If the impairment is significant, it is recommended that appropriate dosage modifications and safety monitoring be implemented by your physician as a precaution.

    Anticholinergic drugs inhibit the parasympathetic nervous system (causing twitches and spasms). Drotaverine helps in reducing the spasms thus inhibiting the parasympathetic activity, hence relieving pain. Drotaverine is an anticholinergic phosphodiesterase 4 inhibitor. Drotaverine has also demonstrated dose-based analgesic effects in animal studies.

    Drotaverine is a spasmodic treatment that alleviates contractions (spasms) in the abdomen in connection with smooth muscles. Diclofenac is an anti-inflammatory non-steroid medication (NSAID). It works by preventing the release of specific symptoms that induce stomach and inflammatory discomfort (swelling).

    According to Tronnes, depending on its safety profile, Drotaverine is deemed to have been 'unclassified medicine'. Recent research, however, believes it to be 'mostly safe' during pregnancy, saying it is among the 10 top medications taken throughout pregnancy. If one is allergic to Drotaverine or any other drugs speak to the doctor before using Drotaverine. The product may include some inactive substances that may cause severe allergic reactions or other issues.

    The effective and safe pharmacological medication for managing the recurring abdomen discomfort in youngsters is Drotaverine hydrochloride. Drotin DS is an antispasmodic medication. It is used for stomach discomfort in youngsters. It offers treatment for irritable bowel syndrome, gut or kidney stones, or other gastrointestinal conditions.

    Drotaverine may be taken either with or after meals as oral medicine. Three times a day, adults may take 40-80 mg, although this will vary with each individual’s medical state. Children aged 1 to 6 years may be given an antispasmodic 20 mg three to four times a day if given orally. In children over six years of age, the dose is usually raised to 40 mg. This therapy helps restore cyclic AMP equilibrium to the calcium ions at the spasm location by preventing the phosphodiesterase IV enzymes in smooth muscles.

    No, in terms of effectiveness, Drotaverine has been considerably better than Mebeverine in reducing pain, frequency, and symptoms in severe cases of IBS. Drotaverine is commonly known with brand names such as Aveine-40, Averine- R or Drot. Colofac, IBS Colofac and Aurobeverine are the brand names for mebeverine. Mebeverine is available in combination with ispaghula husk (fybogel Mebeverine brand name), while Drotaverine is made of 40 mg Drotaverine Hydrochloride.

    • Drotin 2ml helps alleviate pain caused by spasms such as menstruation pain, kidney stone discomfort, and colicky pain.
    • The injection can be taken with or without food.
    • It is administered by a doctor. Do not self-administer.
    • It may cause your blood pressure to fall and cause dizziness.

    Consult our experts at Yashoda hospital in case of any doubts about your condition.

    S.no Product Name Dosage Form
    1. Drotin DS Drotaverine 80mg Tablet
    2. Drotikind Drotaverine 80mg Tablet
    3. DVN Drotaverine 80mg Tablet
    4. Doverin Drotaverine 40mg Tablet
    5. Drotin Drotaverine 80mg Injection